Bentall Surgery in a Patient with Cold Agglutinin and Antiphospholipid Antibody: Double Trouble.

Pyoderma gangrenosum in a patient with antiphospholipid antibody negative systemic lupus erythematosus: A case report

In any description of leg ulcers in systemic lupus erythematosus (SLE), pyoderma gangrenosum (PG) earns a mention at least for its being quite rare in such patients. The causative role of aPL (antiphospholipid antibody) in dermatological manifestations of SLE is undermined by the occurrence of PG in aPL negative SLE patients. To the best of our knowledge, there are only two reports of PG in aPL...

Myocarditis suggesting acute myocardial ischemia, without occlusion of the coronary artery, in a patient with antiphospholipid syndrome and systemic vasculitis in the course of cold agglutinin disease

P46: Optic Neuritis as the First Manifestation of the Primary Antiphospholipid Antibody Syndrome

Optic neuritis is commonly associated with diseases such as Multiple Sclerosis, infections, taking special drugs, etc. but recently we have observed a patient that presented retro bulbar optic neuritis as a manifestation of antiphospholipid syndrome. A 35 y/o young woman with the history of chickenpox admitted to the Qhaem hospital (Mashhad, Iran) with the c/o progressive pain and blurred visio...

آگلوتینین سرد پلاکتی، پدیده ای نادر و در عین حال مهم در آزمایشگاه: گزارش یک مورد ترومبوسیتوپنی کاذب در یک بیمار مبتلا به سرطان کولون

Background: Cold antibody induced platelet clumping is a rare in-vitro phenomenon that causes EDTA independent pseudo thrombocytopenia. This pre-analytical problem leads to a challenge in the clinical laboratory. In such a case platelets tend to easily aggregate in vitro, giving rise to lower platelet counts. The error is detected simply by examining peripheral blood smear. This report describe...

Problems of Cold Agglutinins in Cardiac Surgery: How to Manage Cardiopulmonary Bypass and Myocardial Protection

Cold agglutinins are of unique relevance in cardiac surgerybecause of the use of hypothermic cardiopulmonary bypass (CPB). Cold autoimmune diseases are defined by the presence of abnormal circulating proteins (usually IgM or IgA antibodies) that agglutinate in response to a decrease in body temperature. These disorders include cryoglobulinemia and cold hemagglutinin disease.Immunoglobulin M aut...